Acta Biologica

Wcześniej: Zeszyty Naukowe Uniwersytetu Szczecińskiego. Acta Biologica


ISSN: 2450-8330     eISSN: 2353-3013    OAI    DOI: 10.18276/ab.2021.28-10
CC BY-SA   Open Access   DOAJ

Lista wydań / No. 28
Phytochemical analysis, antioxidant and anticancer activity of Aerva javanica growing in district Karak, Khyber Pakhtunkhwa Pakistan
(Analiza fitochemiczna oraz antyoksydacyjna i przeciwrakowa aktywność Aerva javanica z powiatu Karak, Khyber Pakhtunkhwa Pakistan)

Autorzy: Sajida Afzal ORCID
Kohat University of Science and technology Kohat, Department of Zoology

Siraj Khan ORCID
Department of Botany, Abdulwali Khan University

Majid Iqbal ORCID
Institute of Geographic Science and Natural Resources Research UCAS

Anam Akhtar ORCID
Department of Plant Sciences, Quaid- i- Azam University
Słowa kluczowe: fitochemia potencjał antyoksydacyjny potencjał przeciwnowotworowy analiza GC-MS Aerva javanica
Data publikacji całości:2021
Liczba stron:17 (91-107)
Cited-by (Crossref) ?:

Abstrakt

Celem pracy była ocena fotochemicznej, antyoksydacyjnej i przeciwnowotworowej aktywności rośliny leczniczej Aerva javanica. Ta roślina należy do rodziny Amaranthaceae. Lokalnie nazywa się „bui”. Jest to krzew o długim korzeniu palowym, który dziko rośnie w całych Indiach. Ekstrakty roślinne przygotowano przy użyciu etanolu, metanolu i wody destylowanej jako rozpuszczalników. Aktywność przeciwutleniającą oznaczono za pomocą DPPH (2,2-difenylo-1-pikrylohydrazyl-hydrat) neutralizując wolne rodniki i wyznaczając IC50. Całkowita zawartość związków flawonoidowych znaleziona w ekstrakcie etanolowym Aerva javanica wynosiła (0,90 ±0,16), podczas gdy całkowita zawartość fenoli znaleziona w ekstrakcie etanolowym wynosiła (0,78 ±0,16), a następnie w ekstrakcie metanolowym i wodnym. Wyniki antyoksydacyjne ekstraktu metanolowego z Aerva javanica wykazały 0,78 ±0,18 procent inhibicji, a SCV 49,10% przy stężeniu 1,5 mg/ml, ekstrakt etanolowy wykazał 0,54 ±0,12 procent inhibicji z 64,28% SCV. Analizę fitochemiczną ekstraktu Aerva javanica przeprowadzono techniką chromatografii gazowej ze spektrometrią mas (GC-MS). Wyniki wykazały obecność różnych związków, głównie acetonu (1,18%), octanu etylu (38,95%), (20,77%), octanu n-propylu (4,09%), octanu izobutylu (2,71%), (3,84%), izochinoliny, 1-[(3,4-dietoksyfenylo) metylo]-6,7-dietoksy- (3,36%), cykloheksanon (1,43%), 1,1-diizobutoksy-izobutan (2,02%), kwas n-heksadekanowy (5,61%), fitol (3,57%), kwas 9-oktadecenowy, ester 1,2,3-propanotriylowy (10,72%), kwas oktadekanowy (1,78%), ftalan bis(2-etyloheksylu) (3,48%), skwalen (1,40%), 2,2-dimetylo-3-3,7,16,20-tetrametyl (1,12%) i 1,6,10,14,18,22-tetrakozaheksaen-3-ol (1,195%). Potrzebne są badania mające na celu wykrycie większej liczby nowych związków w celu opracowania skutecznych metod zarządzania, które znacznie zmniejszą wpływ patogenów na zdrowie człowieka, a także na środowisko.
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