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Acta Biologica

Previously: Zeszyty Naukowe Uniwersytetu Szczecińskiego. Acta Biologica

No. 24
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QS – systems communication of Gram-positive bacterial cells

DOI: 10.18276/ab.2017.24-06
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ISSN:2450-8330
Authors: Alicja Ziemichód
University of Szczecin, Department of Genetics, Faculty of Biology

Bogumiła Skotarczak
University of Szczecin, Department of Genetics, Faculty of Biology
Keywords: Quorum sensing Gram-positive bacteria signaling molecules gene expression competence of Streptococcus pneumoniae and Bacillus subtilis virulence of Staphylococcus aureus
Issue / book publication date:2017
Page range:6 (51-56)
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Abstract

In Gram-positive bacteria, cell-to-cell communication, also called quorum sensing (QS) mainly is dependent on extracellular signaling oligopeptide pheromones, which stimulate a response either indirectly, by activating a two-component phosphorelay, or directly, by binding to cytoplasmic effectors. The oligopeptide pheromones production and secretion are initiated in response to specific environmental stimuli or stresses. These pheromones are biosynthesized through different pathways and some have unusual functional chemistry as a result of posttranslational modifications. In the cells of Bacillus subtilis and Streptococcus pneumoniae this system controls the acquisition of the state of competence, while in Staphylococcus aureus it regulates virulence. The review aims at giving an updated overview of these peptide-dependant communication pathways.

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