Central European Journal of Sport Sciences and Medicine
Effect of Supervised Physical Exercise on Oxidative Stress in Children with Autism
DOI: 10.18276/cej.2024.2-04
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| ISSN: | 2300-9705 |
| eISSN: | 2353-2807 |
| Autoren: |
Mehrzad
Moghadasi
Department of physical education, Shiraz branch, Islamic Azad University, Shiraz, Iran Hamid Arvin
Department of physical education, Shiraz branch, Islamic Azad University, Shiraz, Iran Hassan Rohbanfard
Faculty of Sport Sciences‚ Bu-Ali Sina University‚ Hamedan‚ Iran Saeed Arsham
Faculty of Physical Education and Sport Sciences‚ Kharazmi University‚ Tehran‚ Iran Alireza Ostovar
Department of Exercise Physiology, Faculty of Physical Education and Sport Science, University of Guilan, Rasht, Iran |
| Schlüsselbegriffe: | exercise training oxidative stress BDNF malondialdehyde Autism |
| Erscheinungsdatum der Ausgabe / Monografie: | 2024 |
| Seitenanzahl: | 7 (45-51) |
| OAI-PMH: | Metadaten |
| Klasyfikacja JEL: | I19 |
 
 
| |
Abstract
Background: The etiology of autism spectrum disorders is not well known but oxidative stress has been suggested to play a pathological role.
Purpose: The present study aimed to investigate the effects of supervised physical exercise on oxidative stress in children with autism.
Methods: Thirty boys with autism (7 to 9 years old) voluntarily participated in this study. They were randomly divided into experimental and control groups. The experimental group performed a physical curriculum known as sports, play and active recreation for kids (SPARK) for 12 weeks (3 sessions of 45 minutes per week), while the control group was exempted to participate in the program. As the clinical parameters, the level of brain-derived neurotrophic factor (BDNF) and malondialdehyde (MDA) were measured before and after the intervention.
Results: The results indicated that BDNF levels significantly increased (85.7 %) and MDA concentration significantly decreased (29.2%) in the experimental group (p < 0.05).
Conclusions: In conclusion, the supervised physical exercise may result in less oxidative stress in children with autism.
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