Central European Journal of Sport Sciences and Medicine

ISSN: 2300-9705     eISSN: 2353-2807    OAI    DOI: 10.18276/cej.2016.3-02
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Issue archive / Vol. 15, No. 3/2016
The Biological Properties of Lactoferrin

Authors: Grzegorz Trybek
Department of Oral Surgery, Pomeranian Medical University, Szczecin, Poland

Marcin Metlerski
Department of Oral Surgery, Pomeranian Medical University, Szczecin, Poland

Kamila Szumilas
Department of General Pathology, Pomeranian Medical University, Szczecin, Poland

Magda Aniko-Włodarczyk
Department of Oral Surgery, Pomeranian Medical University, Szczecin, Poland

Olga Preuss
Department of Oral Surgery, Pomeranian Medical University, Szczecin, Poland

Katarzyna Grocholewicz
Department of General Dentistry, Pomeranian Medical University, Poland

Barbara Wiszniewska
Department of Histology and Embryology, Pomeranian Medical University, Szczecin, Poland
Keywords: lactoferrin antimicrobial activity immunomodulatory effect
Year of publication:2016
Page range:11 (15-25)
Cited-by (Crossref) ?:


Lactoferrin (LF) is an iron-binding glycoprotein from the transferrin family, which has been identified in most biological fluids as secretions from exocrine glands and the content of specific granules of neutrophils. It has been reported to have numerous functions. Due to antimicrobial and anti-inflammatory activity, the lactoferrin plays significant role in host defense against infection and extreme inflammation. Recent studies have also demonstrated that LF can protect against cancer in experimental animals and has anticarcinogenic activity in many human tumors. At the cellular level, LF modulates the proliferation, differentiation, maturation, activation, migration and function of immune cells. This review presents the multifunctional roles and specific beneficial properties of lactoferrin.
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